Window Shopping: Breast Cancer on CT with Histologic Correlate

Congratulations to Ayelet Beilin, BA, of Montefiore Medical Center at Albert Einstein College for taking home Best Oral Presentation Abstract in Breast Imaging during ARRS 2026. This research on breast cancer detection with contrast-enhanced CT with histologic correlation from Beilin and her colleagues at St. John’s Riverside Hospital in Yonkers suggests “liver windows” significantly improve the accuracy of spotting incidental breast cancer on scans.

Frame of Mind: Mammography remains the gold standard; incidental findings on CT are common. To wit, optimizing the window setting helps rads differentiate actual masses from background noise, reducing unnecessary anxiety and follow-up.

By the numbers:

  • 8%—False-positive rate when using liver windows.
  • 15%—False-positive rate using standard soft-tissue windows.
  • 98%—Rads who preferred using liver windows or a combination of both settings.

RadFYI: Switching to liver windows during CT interpretation can cut false positives nearly in half—without significantly increasing false negatives.

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